Heterogeneity and Dynamics of Vasculature in the Endocrine System During Aging and Disease

The endocrine system consists of several highly vascularized glands that produce and secrete hormones to maintain body homeostasis regulate a range bodily functions processes, including growth, metabolism development. dense capillary network as the main transport for regulatory factors enable efficient function. specialized types provide microenvironments support stem progenitor cells, by regulating their survival, maintenance differentiation. Moreover, vasculature interacts with cells supporting However, structure niche function in tissues remain poorly understood. Aging disorders are associated vascular perturbations. Understanding cellular molecular cues driving disease, age-related perturbations hold potential manage or even treat comorbidities aging. This review aims describe various define changes aging disorders.